SYMPOSIUM
Thursday, November 13
Session I. Ni in Catalysis
6:00p Introductory Comments
6:20 J. G. Reynolds, "Nickel in Petroleum Refining"
7:00 T. Lash, "Synthesis of Geochemically Significant Porphyrins with Fused Carbocyclic Rings."
7:30 D. R. Huntley, "Desulfurization Mechanisms on Single Crystal Nickel Surfaces"
8:00 L. Johnson, "Olefin Polymerizations Catalyzed by Nickel Complexes"
8:30 R. T. Baker, "Applications of Low Valent Nickel Phosphine Complexes to the Preparation of Chlorofluorocarbon (CFC) Alternatives
9:00 V. Pecoraro, "Nickel Metallacrowns: Inorganic Molecular Recognition Agents"
9:30 M. Millar, "The Design and Synthesis of Polydentate Metal-Thiolate Complexes as Functional Models for the Nickel Center in proteins"
10:00 Session Ends
Friday, November 14
Session II. Environmental and Toxicological Aspects, Metabolism
9:00 A. Oller, "Environmental and Toxicological Aspects of Nickel and its Compounds"
9:40 M. Costa, "Molecular Biology of Nickel Carcinogenesis"
10:20 N. Barba-Behrens, "Inhibition Sites of Ni(II) Imidazolic and Benzimidazolic Compounds on Photosynthesis"
10:50 C. Burrows, "Ni(II) Dioxygen Chemistry: Ligand Oxidation and DNA Modification"
11:20 S.-O. Kang, "Superoxide Dismutase Containing Nickel"
11:50 H. L. T. Mobley, "Mechanisms of Nickel Transport in Helicobacter pylori, A Requirement for Synthesis of Cataytically Active Urease Metalloenzyme"
12:30p L.-F. Wu, "Nickel Metabolism in Escherichia coli"
1:00 Session Ends
Session III. Ureases and C1 Biochemistry
3:30p R. P. Hausinger, "Urease Activation and Mechanism"
4:15 G. Soman, "In Vitro Activation of Recombinant Helicobacter pylori Apo- Urease and Blocking of Activation By Chemical Modification or Site-Directed Mutagenesis"
4:45 J. G. Ferry, "The Role of Nickel in Methanogenesis from Acetate"
5:30 R. K. Thauer, "Snapshots through the reaction pathway of methyl-coenzyme M reductase from methanogenic Archaea"
6:00 C. G. Riordan, "Synthetic and Mechanistic Models for CO Dehydrogenase and Methyl Coenzyme M Reductase"
6:30 S. W. Ragsdale, "The Role of Nickel in CO Oxidataion and Acetyl-CoA Synthesis"
7:00 P. A. Lindahl, "Structure and Function of the Nickel and Iron-Sulfur Centers in Carbon Monoxide Dehydrogenase"
7:30 Session ends
Saturday, November 15
Session IV. Hydrogenases
9:00a S. P. J. Albracht, "NiFe(CN)2CO: Biology’s Way To Activate Hydrogen"
9:45 G. Voordouw, "Function of Periplasmic Hydrogenaes in Desulfovibrio"
10:15 J. C. Fontecilla-Camps, "Structural Bases for the Catalytic Mechanism of NiFe Hydrogenases"
10:45 R. Maier, "Nickel-dependent Expression and Maturation of Hydrogenase"
11:15 M. Y. Darensbourg, "Heterobimetallic Complexes in Model Studies for [Ni,Fe] Hydrogenase: Synthetic Approaches to Ni(m-SR)2Fe(CN)2(CO), and its Role in Redox Control of Activity"
11:45 P. Mascharak, "Reactions of Hydrogen and CO with Nickel Complexes Containing [NiN3E2] (E = S, Se) Chromophores: Relevance to [Ni,Fe] Hydrogenases."
12:15 M. J. Maroney, "Comments on the Hydrogenase Mechanism from Biophysical and Model Studies"
12:45p Closing remarks
1:00 Session Ends