Nov 11-15, 1997. Cancun, Quintana Roo, Mexico
SYMPOSIUM
9:00 a.m. ______ The Nutritional Essentiality and Physiological
Metabolism of Vanadium in Higher Animals. F. H. Nielsen
9:30 a.m. ______ Studies of Vanadate-Organic Ligand Systems
Using Potentiometry and NMR Spectroscopy. L. Pettersson
10:00 a.m. ______ Structural and Functional Models for Biogenic Vanadium Compounds. D. Rehder, M. Bashirpoor, S. Jantzen, H. Schmidt
10:30 a.m. ______ Synthesis, Structure and Reactivity of V(V)-Thiolate and V(V)-eta2-Sulfenate Complexes. C. R. Cornman, T. C. Stauffer, P. D. Boyle
10:50 a.m. ______ Selective Synthetic Transformations via
Vanadium-Induced Redox. T. Hirao
11:10 a.m. Intermission
11:20 a.m. ______ Vanadyl Cation as a Probe of Nucleotide and Protein Structure. S. Chen, H. Ruetthard, A. Banerjee, F. S. Jiang, M. Sprinzi, M. W. Makinen
11:50 a.m. ______ The Vanadyl Coordination Environment in Imidazole Glycerol Phosphate Dehydratase. J. Petersen, T. R. Hawkes, D. J. Lowe
12:10 p.m. ______ The Accumulation Mechanism of Vanadium by
Ascidians. H. Michibata, T. Uyama, K. Kanamori
3:30 p.m. ______ Chloroperoxidase from Curvularia inaequalis: X-Ray Structures of Native and Peroxide Form Reveal Vanadium Chemistry in Vanadium Haloperoxidases. A. Messerschmidt, L. Prade, R. Wever
3:50 p.m. ______ Peroxidase Activity of Vanadium Haloperoxidase Model Compounds. C. Slebodnick, M. E. Gillis, B. J. Hamstra, V. L. Pecoraro
4:20 p.m. ______ Selectivity of Vanadium Bromoperoxidase with
Indole Derivatives. A. Butler, A. Baldwin, M. Simpson
4:50 p.m. ______ From Vanadium Haloperoxidases to Phosphatases, the Same Architecture for the Active Site. R. Wever, W. Hemrika, R. Renirie, P. Barnett, A. Messerschmidt, Henk Dekker
5:10 p.m. Intermission
5:20 p.m. ______ A New Class of Insulin-Mimetic Compounds: N,N-Dimethylhydroxamidovanadates, Aspects of Their Chemistry and Function. F. Nxumalo, A. S. Tracey
5:50 p.m. ______ New Peroxo- and Hydroxylamino Vanadium Complexes: Chemistry, Phosphatase Activity and Insulin Mimetic Properties. D. C. Crans
6:20 p.m. ______ Paradoxical Enhanced Sensitivity of Insulin Resistant Adipocytes to Vanadate is Associated with Decreased Intracellular Reduction of Vanadate(+5) to Vanadyl(+4). I. G. Fantus, B. Lu
6:40 p.m. ______ Vanadyl Sulfate (VS)-Induced Glycogen Synthesis in Chinese Hamster Ovary Cells Over-expressing Human Insulin Receptor (CHO-HIR Cells) is Blocked by Wortmannin and LY294002, Inhibitors of Phosphatidyl Inositol 3-Kinase (PI3-K). S. K. Pandey, M. B. Anand-Srivastava, A. K. Srivastava
9:00 a.m. ______ Coordination Chemistry of Insulin-Mimetic Vanadium Compounds. C. Orvig, J. H. McNeill
9:30 a.m. ______ On the Insulin-Like Effects of Vanadium Salts. Y. Shechter, E. Elberg, N. Sekar, Z.-B. He, D. Gefel, J. Meyerovitch, R. Bruck, E. Gershonov, A. Shishevia, D. C. Crans, R. Sigar, M. Fridkin, Y. Goldwasser, J. Li
10:00 a.m. Intermission
10:10 a.m. ______ Vanadium Bioactivity on Cells in Culture. S.
B. Etcheverry, A. M. Cortizo
10:40 a.m. ______ Mechanism of Action of Peroxovanadium
Compounds. B. I. Posner, A. Shaver
11:10 a.m. ______ Structure-Activity Relationships of the
Insulin-Mimetic Vanadyl Complexes. H. Sakurai
11:40 a.m. ______ Pharmacokinetics of Vanadium Following Repeated Oral Dosing with Vanadyl Sulfate in Patients with NIDDM. G. R. Willsky, A. B. Goldfine, C. R. Kahn, P. J. Kostyniak
12:00 p.m. ______ Vanadium Salts in the Treatment of Human
Diabetes Mellitus. C. R. Kahn, A. B. Goldfine
Alan S. Tracey, Presiding
7:30 - 10:00 PM
___ Vanadium(V) Equilibria: Stability Constants and Thermodynamic
Quantities for the Various Ionic Species. J. J. Cruywagen
___Estimating Formation Constants for Vanadium(V)-Pentose
Complexes. D. C. Crans, F. Xin
___ Solution Chemistry of Bis(1,2-dimethyl-3-hydroxy-4-pyridinonate)oxo-vanadium(IV) in Water. M. Rangel, M. Castro, W. Schlindwein, R. Matias, B. Castro, C. Geraldes, J. Burgess
____ Synthesis and Characterization of Trigonal Bipyramidal Vanadyl Complexes: Structural and Electronic Constants on Molecular Geometry. C. R. Cornman, K. M. Geiser-Bush, P. D. Boyle
___ Reactions of Vanadate with Thiol Compounds: Complex Formation
and Redox Chemistry. D. C. Crans, B. Zhang
___ Composition and Structure of Vanadium(V) Peroxo Complexes. P. Schwendt, M. Sivak
___ From the Speciation of Peroxovanadium Complexes in Aqueous Solution to the Chemistry of Haloperoxidases. V. Conte, F. Di Furia, S. Moro
___ Bis(peroxo)oxovanadium(V) Complexes of Histidine-Containing Peptides as Models for Vanadium Halo-peroxidases. J. A. Guevara-Garcia, G. Mendoza-Diaz and N. Barba-Behrens
___ Vanadium Chloroperoxidase Models: Solvent Dependence of Chloride Oxidation Rates by Vanadate. C. Slebodnick, G. J. Colpas, V. L. Pecoraro
___ Catalytic Oxidations with Biomimetic Vanadium Systems. I. W.
Arends, R. A. Sheldon
___ The Applications of Vanadium Peroxidases as Novel Biocatalysts. H. B. ten Brink, W. Hemrika, H. L. Dekker, H. E. Schoemaker, R. Wever
___ Exploring the Active Site of Vanadium Chloroperoxidase. R.
Renirie, W. Hemrika, H. L. Dekker, P. Barnett, R. Wever, E. C. Slater
___ A Possible Role for Amavadine in Some Amanita Fungi. C. M. M. Matoso, A. J. L. Pombeiro, J. J. R. Frausto da Silva, M. F. C. Guedes da Silva, J. A. L. Silva
___ What is the Active Vanadium Species Inhibiting Growth of S. cerevisiae in High Phosphate Growth Medium? G. R. Willsky, D. C. Crans
___ Determination of the Vanadate-Mediated NAD(P)H or NADH Oxidation Mechanism by Superoxide Radical. I. Nieves-Martinez, C. J. Olivo-Delgado, R. P. Mason
___ Influence of Vanadate on Glycolysis, Intracellular Sodium and pH in Perfused Rat Hearts. C. F. G. C. Geraldes, M. M. C. A. Castro, R. Ramasamy, A. D. Sherry
___Vanadate and Pervanadate Stimulate Glucose Uptake in L6 Skeletal Muscle Cells by a Mechanism Independent on Phosphatidylinositol 3-Kinase and Protein Kinase. I. G. Fantus, E. Tsiani, A. Sorisky
___ New Vanadium Compounds in The Treatment of Diabetes-Induced Rats. J. A. Guevara-Garcia, E. B. Colombres, E. Gonzalez-Vergara, R. Tapia-Benavides, C. E. Weinmann
Further information concerning the Fifth NACC can be obtained from the ACS webpage http://www.acs.org/meetings/5nacc
The organizers of this symposium may be contacted for further
information:
Debbie C. Crans crans@lamar.colostate.edu
Colorado State University
Alan S. Tracey tracey@sfu.ca
Simon Fraser University
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Alan S. Tracey Department of Chemistry and Institute of Molecular Biology and Biochemistry Simon Fraser University Burnaby, B.C., V5A 1S6 Canada --------- Tel (604) 291 4464 FAX (604) 291 3765 e_mail tracey@sfu.ca